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By Mervyn Richardson

Dimension of the level of the poisonous insult attributable to the substance concerned is of significance while venture an environmental toxicology evaluate. this article outlines many of the dimension thoughts which have been lately constructed and

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2. P. H. B. ), Springer, New York, 1981, 10–23. 3. P. Science 1969, 164, 262–270. 4. V. Physiological Reviews 1980, 60, 1107–1165. 5. ‘Biomarkers of the nervous systems’, In: Animal Biomarkers as Pollution Indicators. Ecotoxicology Series I, Peakall, D. ), Chapman and Hall, 1992, 20–45. 6. Zedachift fürWasser-Abwasser-Forschung 1989,22, 67–72. 7. ‘Cholinesterase-hemmtest’ In: Biochemische Methoden zur Schadstofferfassung im Wasser— Möglichkeiten und Grenzen, Hrsg. O. ), VCH Verlagsgesellschaft, Weinheim, 1993.

Aquatic plants are able to bioconcentrate organic (and inorganic pollutants) and provide biochemical responses. Quantitative structural activity relationships (QSARs) have a great future, especially when applied to interspecies relationships. New techniques on mobility inhibition using microplates and flow cytometry are exciting new prospects. 3 The application of measuring techniques These are illustrated by the action being taken by the international agencies within developing countries, especially in the fields of agroecotoxicology, monitoring of industrial effluents and in the application of biodegradation testing.

Biological measurement techniques for environmental toxicology have been increasing in availability and scope over the past ten years and their attraction is of obvious advantage and such techniques, unlike chemical methods, provide an indication of the toxicity of the sample investigated. 3 Whilst such techniques will not indicate which substances in such complex mixtures are toxic, they do provide a very rapid indication of the environmental toxicity of a sample. A number of new and exciting variations of such biological measuring techniques are now in the course of development, eg, EROD, cytochrome P-450 activation, umu assay, spindle unwinding, DNA probes, etc, and the development of these techniques will surely lead to the concept of toxic insult.

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